Ahmed Badawy
Neonatal Specialist, Tertiary Care Neonatal Intensive Care Unit (NICU), Saudi Arabia.
Title: Impact of Preeclampsia on Newborn Babies
Biography
Biography: Ahmed Badawy
Abstract
Preeclampsia is considered as an obstetric clinical syndrome with an unclear etiology, a genetic component, and a complex pathophysiology, which involves maternal and fetal vascular alterations that could persist and cause diseases in later life.
Multifactorial polygenic inheritance is presumed, as it shows familial predisposition, geographical and racial variability, as well as, various PE-related genes and polymorphisms that have been identified.
Although its pathophysiology is complex and incompletely understood, it is adopted that placenta (placentopathy) is a triggering organ in the disease development.
Preeclampsia is associated with early and late unfavorable neonatal outcomes, predominantly, due to increasing indications for preterm delivery, which In turn has a major impact on neonatal mortality and morbidity, hence considered as a determinant factor in neonatal prognosis.
Prematurity and IUGR are by far the most common implications of preeclampsia. Even though the relation between Preeclampsia and short & long term neonatal outcomes is controversial in the literature, recent studies mostly are supporting, collectively, the unfavorable outcomes.